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Results for "

Colon motility

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116522
    AR420626
    2 Publications Verification

    		 Free Fatty Acid Receptor Others
    AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3, GPR41) with IC50 of 117 nM. AR420626 inhibits nicotine and serotonin-induced changes in motility of isolated muscle strips from rat colon and suppresses serotonin-induced fecal output in rats .
    AR420626
  • HY-B0544
    Sodium Picosulfate

    Sodium Picosulphate

    		 Others Metabolic Disease
    Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .
    Sodium Picosulfate
  • HY-15790
    Elobixibat

    A 3309; AZD 7806

    		 Apical Sodium-Dependent Bile Acid Transporter Interleukin Related TNF Receptor Metabolic Disease Inflammation/Immunology
    Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors .
    Elobixibat
  • HY-106323
    [Leu13]-Motilin

    KW-5139

    		 Motilin Receptor Metabolic Disease
    [Leu13]-Motilin (KW-5139) is a motilin analogue. [Leu13]-Motilin stimulates gastrointestinal motility in the rabbit. [Leu13]-Motilin causes concentration-dependent contractions of the gastric antrum, duodenum, jejunum, ileum and the descending colon in vitro .
    [Leu13]-Motilin
  • HY-14441
    ML 10302

    		5-HT Receptor Neurological Disease
    ML 10302 is a potent agonist 5-HT4 receptor with Ki of 1.07 nM. 5-Hydroxytryptamine (5-HT4) receptor agonists stimulate gut motility through cholinergic pathways. ML10302 induces significant prokinesia both in the small bowel and colon through activation of cholinergic pathways. ML 10302 also has the potential for the research of neurology diseases .
    ML 10302

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